Did you ever wonder: Hey, the original SARS outbreak was 15 years ago, why don’t we just use the SARS vaccine we put our (and every...

The early days of the COVID-19 pandemic have seen a rush to repurpose existing approved or near approval drugs, due to the urgency of the...

Imagine you had a drug that dramatically improved the symptoms or signs of a disease in 70% of the patients who take it, but carried the...

It seems like an obvious concept: Let's say you are developing a drug that works by inhibiting, say, phosphodiesterase-4 (PDE-4) to treat...

After the euphoria of the discovery of the viral cause of AIDS (1984) came the growing (e.g. Dallas Buyer’s Club) desperation as that...

The holy grail of the pharma industry is FDA approval, but the final clue may be positive top-line (Phase III) results. However, it is...

We waited a long time for a real gene therapy, though we were promised it would be easy. So now we are feeling optimistic about the other...

In any competitive sport, you know that what worked one time down the field/floor/ice is VERY unlikely to work again the second time. We...

There are drug adverse events, and then there are the Voldemorts of drug adverse effects, whose which-must-not-be-named. Bleeding in...

Just when you thought you were out, they pull you back in. We in the business obsess over the “valley of death” and the drug development...