November 20, 2018

It’s long been known that better early prediction of drug-like compound properties overcomes costly drug attrition later.  But prediction is stuck in the dark ages.  In this essay from the last decade, Dr. Malcolm Young entertainingly likens the potentia...

October 18, 2018

Some autoimmune diseases, like lupus, affect multiple tissues, but some, like inflammatory bowel disease, affect only specific types.  A new study reveals that HDAC7 controls tissue-specific autoimmunity in othertissues via its action in the thymus, a mechanism which y...

August 29, 2018

The overlap between seasonal allergies, asthma and eczema has long been recognized. All three are treated by antihistamines, for example, and their histologies match as well, with eosinophils (a type of white blood cell) migrating from the blood into the skin (eczema),...

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