Plaque Mark
The recent earthquake in the Alzheimer’s drug field is causing the usual periodicreview and reaffirmation of our general process of drug...
Relief belief
Eureka! We've found . . . out that we were awarded a grant from the National Institute on Drug Abuse (NIDA). In the coming year, using...
Sick factor
The SARS-CoV-2 coronavirus that causes COVID-19 disease is an enveloped virus. Meaning, it is mostly human plasma membrane, with a few...
Fast and spurious
Did you ever wonder: Hey, the original SARS outbreak was 15 years ago, why don’t we just use the SARS vaccine we put our (and every...
Screen stars
Necessity is said to be the mother of invention, but the jury is still out on the success of the desperate and rushed phenotypic screens...
Nucleic freeze
While the protease inhibitor flopped for COVID-19, that doesn’t mean that the line of reasoning of drugs cross-reactive with viral...
Surface charm
A small pilot study from France showed that all six COVID-19 patients given a hydroxychloroquine/azithromycin combination recovered...
Target practice
The early days of the COVID-19 pandemic have seen a rush to repurpose existing approved or near approval drugs, due to the urgency of the...
Auld ligands syne
The massive inefficiency of target-based high-throughput screening eventually led to major pivots in the pharmaceutical industry. The...
Screen scene
In contrast to target-based strategies, phenotypic drug discovery does not rely on knowledge of a specific drug target or a hypothesis...